I take it you don't write much maths then? Most of the macros I define are to make the process of writing maths faster, easier and more correct (common expressions become short macros, macros for specific semantics etc.), and the lack of amsmath-equivalent means that Typst loses out on a major part of its audience.

The "reasonably normal programming language" part is a turn-off for non-software-devs, and for software devs I'm not sure why I wouldn't generate LaTeX via something like jinja2, or directly create PDFs with reportlab.