I use TweetDeck. It's like the power user version of Twitter. I generally have 20+ columns on my screen at any given time.
Most of the people I follow I found through people I know retweeting them or through looking at the feeds of other successful/important people (for example, I recreated the feeds of other investors/entrepreneurs) - http://theireyes.austenallred.com/
Most of the people I follow I found through people I know retweeting them or through looking at the feeds of other successful/important people (for example, I recreated the feeds of other investors/entrepreneurs) - http://theireyes.austenallred.com/